J-113863

CAT: 1410-M22691-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M22691-01Size:1 g
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Description
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM), but a weak antagonist of the mouse CCR3 (IC50 of 460 nM) . J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively.
CAS Number
353791-85-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
655.44
Molecular Formula
C30H37Cl2IN2O2
Notes
Research use only, not for human use.
Receptor
CCR1|CCR3

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