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Trans-J-113863

CAT: 0013-GTR19233323-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233323-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trans-J-113863 is a potent dual antagonist of chemokine receptors CCR1 and CCR3, with IC50 values of 9.57 nM and 93.8 nM against MIP-1α and eotaxin-induced chemotaxis, respectively. It is a valuable research tool for studying allergic inflammation, asthma, and other CCR1/CCR3-mediated pathways in both cellular and animal models.
CAS Number
202796-42-7
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C (N[C@@H]1CC[N@+] (CC=2CCCCCCC2) (CC) CC1) (=O) C3C=4C (OC=5C3=CC (Cl) =CC5) =CC=C (Cl) C4.[I-]
Molecular Formula
C30H37Cl2IN2O2
Molecular Weight
655.44
Storage Conditions
-20°C
Notes
For research use only.

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