DS-6051b

• Description:

  DS-6051b is a new-generation selective inhibitor of ROS1/NTRK including ROS1, NTRK1, NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.DS-6051b inhibited the growth of the ROS1 fusion-positive HCC78 cancer cell line and the CD74-ROS1 overexpressed Ba/F3 cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  551.61

• Molecular Formula:

  C29H34FN5O5

• Notes:

  Research use only, not for human use.

• Receptor:

  ROS1| TrkA| TrkB| TrkC

• CAS Number:

  1505515-69-4