CC-92480

• Description :

  CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD) with potent antimyeloma activity.CC-92480-induced loss of Aiolos and Ikaros in cultures of PBMCs resulted in the activation of T cells and increased production of IL-2 and IFN-γ. It exerts single-agent induction of apoptosis and exhibits remarkable synergy with NSC 34521. CC-92480 is effective in CC-4047, CC-5013, and CC-220-resistant cell lines.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  567.61

• Molecular Formula :

  C32H30FN5O4

• Notes :

  Research use only, not for human use.

• Receptor :

  E1/E2/E3 Enzyme

• CAS Number :

  2259648-80-9