BAY-985

• Description:

  BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.BAY-985 inhibits FLT3, RSK4, DRAK1, and ULK1 (IC50s: 123, 276, 311, and 7930 nM) . BAY-985 inhibits the cellular phosphorylation of interferon regulatory factor 3 (IRF3, IC50: 74 nM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  553.58

• Molecular Formula:

  C27H30F3N9O

• Notes:

  Research use only, not for human use.

• Receptor:

  TBK1|TBK1|IKKε

• CAS Number:

  2409479-29-2