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HLM006474

CAT: 1410-M22127-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M22127-01Size:1 Each
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Description
HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 µM in A375 cells) .HLM006474 causes the viability of both SCLC and NSCLC lines (IC50 ranging from 15 to 75 µM) . HLM006474 displays little activities against E2F4 DNA-binding in A375 cells at 10 and 20 µM, apparently inhibits E2F4 DNA-binding at 40 µM, and increasingly suppresses the effect at 60 and 80 µM concentrations.
CAS Number
353519-63-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
399.48
Molecular Formula
C25H25N3O2
Notes
Research use only, not for human use.
Receptor
E2F4 DNA-binding