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SP 141

CAT: 1410-M22094-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M22094-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.SP141, which bound directly to MDM2, promoting its auto-ubiquitination and degradation by the proteasome.
CAS Number
1253491-42-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
324.38
Molecular Formula
C22H16N2O
Notes
Research use only, not for human use.
Receptor
Mdm2

Chemical Information

6-methoxy-1-(naphthalen-1-yl)-9H-pyrido(3,4-b)indole

an MDM2 inhibitor with antineoplastic activity; structure in first source

CAS Number1253491-42-7
PubChem CID59620153
IUPAC Name6-methoxy-1-naphthalen-1-yl-9H-pyrido[3,4-b]indole
Molecular FormulaC22H16N2O
Molecular Weight324.4
XLogP5.2
Topological Polar Surface Area37.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Heavy Atom Count25
Formal Charge0
Complexity469
SMILES
COC1=CC2=C(C=C1)NC3=C2C=CN=C3C4=CC=CC5=CC=CC=C54
InChI
InChI=1S/C22H16N2O/c1-25-15-9-10-20-19(13-15)18-11-12-23-21(22(18)24-20)17-8-4-6-14-5-2-3-7-16(14)17/h2-13,24H,1H3
InChIKey
AABFWJDLCCDJJN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-methoxy-1-(naphthalen-1-yl)-9H-pyrido(3,4-b)indole
CAS: 1253491-42-7
CID: 59620153
Formula: C22H16N2O
MW: 324.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight324.4
XLogP35.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass324.126263138
Monoisotopic Mass324.126263138
Topological Polar Surface Area37.9 Ų
Heavy Atom Count25
Formal Charge0
Complexity469
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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