SP-100030

• Description:

  SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and other T cell lines. Additionally, SP-100030 has been shown to decrease the severity of murine collagen-induced arthritis (CIA) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  437.65

• Molecular Formula:

  C14H5ClF9N3O

• Notes:

  Research use only, not for human use.

• Receptor:

  NF-κB

• CAS Number:

  154563-54-9