Products for Research Use Only

MAZ51

CAT: 1410-M21948-02Size: 2 mgDry Ice: NoHazardous: No
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CAT#:1410-M21948-02Size:2 mg
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Description
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. MAZ51 is able to block the proliferation of VEGFR-3-expressing human endothelial cells and is less potently able to induce their apoptosis.
CAS Number
163655-37-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
314.38
Molecular Formula
C21H18N2O
Notes
Research use only, not for human use.
Receptor
VEGFR3

Chemical Information

3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one
CAS Number163655-37-6
PubChem CID24906291
IUPAC Name3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one
Molecular FormulaC21H18N2O
Molecular Weight314.4
XLogP4.3
Topological Polar Surface Area32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity512
SMILES
CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
InChI
InChI=1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)
InChIKey
VFCXONOPGCDDBQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one
CAS: 163655-37-6
CID: 24906291
Formula: C21H18N2O
MW: 314.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight314.4
XLogP34.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass314.141913202
Monoisotopic Mass314.141913202
Topological Polar Surface Area32.3 Ų
Heavy Atom Count24
Formal Charge0
Complexity512
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count1
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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