AMG-47a

• Description:

  AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  535.56

• Molecular Formula:

  C29H28F3N5O2

• Notes:

  Research use only, not for human use.

• Receptor:

  Lck

• CAS Number:

  882663-88-9