WYE-687

• Description:

  WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  528.61

• Molecular Formula:

  C28H32N8O3

• Notes:

  Research use only, not for human use.

• Receptor:

  MTOR , PI3Kα , PI3Kγ , p38α , Src

• CAS Number:

  1062161-90-3