WYE-687

• Description :

  WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) .

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  528.61

• Molecular Formula :

  C28H32N8O3

• Notes :

  Research use only, not for human use.

• Receptor :

  MTOR , PI3Kα , PI3Kγ , p38α , Src

• CAS Number :

  1062161-90-3