VX-809

• Description :

  VX-809 (Lumacaftor, VRT 826809) is a potent CFTR corrector that increases F508del-CFTR-mediated chloride transport amd improves F508del-CFTR maturation in FRT cells with EC50 of 0.1 and 0.5 uM, respectively.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  452.41

• Molecular Formula :

  C24H18F2N2O5

• Notes :

  Research use only, not for human use.

• Receptor :

  F508del-CFTR

• CAS Number :

  936727-05-8