VX-745

• Description :

  A potent and selective p38α kinase inhibitor with IC50 of 9 nM; shows 20-fold selectivity for p38α over p38β (Ki=220 nM) and no significant inhibition for MAP kinases (with the exception of MKK6) .

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  436.2621

• Molecular Formula :

  C19H9Cl2F2N3OS

• Notes :

  Research use only, not for human use.

• Receptor :

  P38α|p38β

• CAS Number :

  209410-46-8