VX-745

• Description:

  A potent and selective p38α kinase inhibitor with IC50 of 9 nM; shows 20-fold selectivity for p38α over p38β (Ki=220 nM) and no significant inhibition for MAP kinases (with the exception of MKK6) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  436.2621

• Molecular Formula:

  C19H9Cl2F2N3OS

• Notes:

  Research use only, not for human use.

• Receptor:

  P38α|p38β

• CAS Number:

  209410-46-8