Products for Research Use Only

ASP 8477

CAT: 1410-M16516Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M16516Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A novel potent, highly selective fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 0.99, 1.65 and 57.3 nM for human FAAH-1, FAAH-1 (P129T) and FAAH-2, respectively.
CAS Number
906737-25-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
325.368
Molecular Formula
C18H19N3O3
Notes
Research use only, not for human use.
Receptor
FAAH

Chemical Information

Asp-8477

a small molecule, orally active inhibitor of the fatty acid amide hydrolase enzymes FAAH and FAAH-2, that is active in vitro and in vivo

CAS Number906737-25-5
PubChem CID15950844
IUPAC Namepyridin-3-yl 4-(phenylcarbamoyl)piperidine-1-carboxylate
Molecular FormulaC18H19N3O3
Molecular Weight325.4
XLogP1.9
Topological Polar Surface Area71.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity429
SMILES
C1CN(CCC1C(=O)NC2=CC=CC=C2)C(=O)OC3=CN=CC=C3
InChI
InChI=1S/C18H19N3O3/c22-17(20-15-5-2-1-3-6-15)14-8-11-21(12-9-14)18(23)24-16-7-4-10-19-13-16/h1-7,10,13-14H,8-9,11-12H2,(H,20,22)
InChIKey
PLCMZPFTMOAGOE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Asp-8477
CAS: 906737-25-5
CID: 15950844
Formula: C18H19N3O3
MW: 325.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight325.4
XLogP31.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass325.14264148
Monoisotopic Mass325.14264148
Topological Polar Surface Area71.5 Ų
Heavy Atom Count24
Formal Charge0
Complexity429
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes