Afatinib dimaleate

• Description:

  An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  718.0827

• Molecular Formula:

  C32H33ClFN5O11

• Notes:

  Research use only, not for human use.

• Receptor:

  EGFR (L858R) |EGFR (L858R/T790M) |EGFR (wt) |HER2

• CAS Number:

  850140-73-7