Afatinib

• Description:

  An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  485.9384

• Molecular Formula:

  C24H25ClFN5O3

• Notes:

  Research use only, not for human use.

• Receptor:

  EGFR

• CAS Number:

  850140-72-6