Tofacitinib citrate

• Description :

  A potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays; displays 20- to 100-fold less potency for JAK2 and JAK1 (IC50=20 nM and 112 nM, respectively) .

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  504.4931

• Molecular Formula :

  C22H28N6O8

• Notes :

  Research use only, not for human use.

• Receptor :

  JAK1|JAK2|JAK3|Lck|ROCK2

• CAS Number :

  540737-29-9