Tofacitinib

• Description:

  Tofacitinib (CP-690550) is a potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays; displays 20- to 100-fold less potency for JAK2 and JAK1 (IC50=20 nM and 112 nM, respectively) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  312.37

• Molecular Formula:

  C16H20N6O

• Notes:

  Research use only, not for human use.

• Receptor:

  JAK1|JAK2|JAK3|Lck|ROCK2

• CAS Number:

  477600-75-2