SU-9516

• Description:

  A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4 (IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  241.2453

• Molecular Formula:

  C13H11N3O2

• Notes:

  Research use only, not for human use.

• Receptor:

  CDK1|CDK2|CDK4|p38|PKC

• CAS Number:

  377090-84-1