NS6180

CAT: 1410-M14204-02Size: 5 mgDry Ice: NoHazardous: No

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CAT#:1410-M14204-02Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NS6180 is a novel potent and selective KCa3.1 channel inhibitor (IC50= 9 nM) prevents T-cell activation and inflammation.

CAS Number

353262-04-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

323.33

Molecular Formula

C16H12F3NOS

Notes

Research use only, not for human use.

Receptor

KCa3.1 channel

Chemical Information

NS6180

CAS Number	353262-04-1
PubChem CID	11837221
IUPAC Name	4-[[3-(trifluoromethyl)phenyl]methyl]-1,4-benzothiazin-3-one
Molecular Formula	C16H12F3NOS
Molecular Weight	323.3
XLogP	4
Topological Polar Surface Area	45.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Heavy Atom Count	22
Formal Charge	0
Complexity	415

SMILES

C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F

InChI

InChI=1S/C16H12F3NOS/c17-16(18,19)12-5-3-4-11(8-12)9-20-13-6-1-2-7-14(13)22-10-15(20)21/h1-8H,9-10H2

InChIKey

ZUIJXKLTUFCDGO-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 353262-04-1

CID: 11837221

Formula: C16H12F3NOS

MW: 323.3

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	323.3
XLogP3	4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	323.05916967
Monoisotopic Mass	323.05916967
Topological Polar Surface Area	45.6 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	415
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes