Sorafenib

• Description:

  A potent, orally available Raf inhibitor with IC50 of 6, 22, and 38 nM for Raf-1, wt Braf, and BRaf V599E, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  464.825

• Molecular Formula:

  C21H16ClF3N4O3

• Notes:

  Research use only, not for human use.

• Receptor:

  B-Raf|B-Raf (V599E) |Raf-1|VEGFR2/Flk1|VEGFR3

• CAS Number:

  284461-73-0