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Gefitinib-based PROTAC 3

CAT: 1410-M13575-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M13575-01Size:1 Each
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Description
Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R) .
CAS Number
2230821-27-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
934.522
Molecular Formula
C47H57ClFN7O8S
Notes
Research use only, not for human use.
Receptor
PROTAC

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MBS3603574-01Gefitinib-based PROTAC 3
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