Capzimin

CAT: 1410-M13248-01Size: 1 EachDry Ice: NoHazardous: No

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CAT#:1410-M13248-01Size:1 Each

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Description

Capzimin (Rpn11 inhibitor 3027) is a derivative of 8TQ, and potent and specific inhibitor of proteasome isopeptidase Rpn11 with IC50 of 0.34 uM.

CAS Number

2084867-65-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

315.409

Molecular Formula

C15H13N3OS2

Notes

Research use only, not for human use.

Receptor

Proteasome

Chemical Information

8-Mercapto-N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide

CAS Number	2084867-65-0
PubChem CID	124081114
IUPAC Name	8-sulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamide
Molecular Formula	C15H13N3OS2
Molecular Weight	315.4
XLogP	2.6
Topological Polar Surface Area	84.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	21
Formal Charge	0
Complexity	369

SMILES

C1=CC2=CC(=CN=C2C(=C1)S)C(=O)NCCC3=NC=CS3

InChI

InChI=1S/C15H13N3OS2/c19-15(17-5-4-13-16-6-7-21-13)11-8-10-2-1-3-12(20)14(10)18-9-11/h1-3,6-9,20H,4-5H2,(H,17,19)

InChIKey

MYNGHZGMRXNEEH-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2084867-65-0

CID: 124081114

Formula: C15H13N3OS2

MW: 315.4

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	315.4
XLogP3	2.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	315.05000439
Monoisotopic Mass	315.05000439
Topological Polar Surface Area	84.1 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	369
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes