Capzimin

• Description:

  Capzimin is a potent and moderately specific proteasome isopeptidase Rpn11 inhibitor.

• UNSPSC:

  12352005

• Target:

  Deubiquitinase; Proteasome

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Capzimin.html

• Concentration:

  10mM

• Purity:

  99.19

• Solubility:

  DMSO : ≥ 55.67 mg/mL

• Smiles:

  O=C(C1=CC2=CC=CC(SSC3=C4N=CC(C(NCCC5=NC=CS5)=O)=CC4=CC=C3)=C2N=C1)NCCC6=NC=CS6

• Molecular Formula:

  C30H24N6O2S4

• Molecular Weight:

  628.81

• References & Citations:

  [1]Li J, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017 May;13 (5) :486-493.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2084868-04-0]