Capzimin

• Description :

  Capzimin is a potent and moderately specific proteasome isopeptidase Rpn11 inhibitor.

• UNSPSC :

  12352005

• Target :

  Deubiquitinase; Proteasome

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Capzimin.html

• Concentration :

  10mM

• Purity :

  99.19

• Solubility :

  DMSO : ≥ 55.67 mg/mL

• Smiles :

  O=C(C1=CC2=CC=CC(SSC3=C4N=CC(C(NCCC5=NC=CS5)=O)=CC4=CC=C3)=C2N=C1)NCCC6=NC=CS6

• Molecular Formula :

  C30H24N6O2S4

• Molecular Weight :

  628.81

• References & Citations :

  [1]Li J, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017 May;13 (5) :486-493.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2084868-04-0]