THZ-1

• Description :

  A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM; displays broad-based activity a subset of cancer cell lines with IC50s of <200 nM.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  566.0527

• Molecular Formula :

  C31H28ClN7O2

• Notes :

  Research use only, not for human use.

• Receptor :

  CDK7

• CAS Number :

  1604810-83-4