THZ-1

• Description:

  A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM; displays broad-based activity a subset of cancer cell lines with IC50s of <200 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  566.0527

• Molecular Formula:

  C31H28ClN7O2

• Notes:

  Research use only, not for human use.

• Receptor:

  CDK7

• CAS Number:

  1604810-83-4