Products for Research Use Only
RegisterLogin

EBI-907

CAT: 1410-M12260-04Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M12260-04Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EBI-907 is a highly potent, selective, orally active B-Raf V600E inhibitor with enzyme IC50 of 7 nM, A375 cell growth IC50 of 13 nM.
CAS Number
1581764-31-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
506.95
Molecular Formula
C23H21ClF2N4O3S
Notes
Research use only, not for human use.
Receptor
Raf

Chemical Information

N-(2-chloro-3-(1-cyclopropyl-8-methoxy-3H-pyrazolo[3,4-c]isoquinolin-7-yl)-4-fluorophenyl)-3-fluoropropane-1-sulfonamide
CAS Number1581764-31-9
PubChem CID73427153
IUPAC NameN-[2-chloro-3-(1-cyclopropyl-8-methoxy-2H-pyrazolo[3,4-c]isoquinolin-7-yl)-4-fluorophenyl]-3-fluoropropane-1-sulfonamide
Molecular FormulaC23H21ClF2N4O3S
Molecular Weight507.0
XLogP4.6
Topological Polar Surface Area105
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count34
Formal Charge0
Complexity817
SMILES
COC1=C(C=C2C=NC3=NNC(=C3C2=C1)C4CC4)C5=C(C=CC(=C5Cl)NS(=O)(=O)CCCF)F
InChI
InChI=1S/C23H21ClF2N4O3S/c1-33-18-10-14-13(11-27-23-20(14)22(28-29-23)12-3-4-12)9-15(18)19-16(26)5-6-17(21(19)24)30-34(31,32)8-2-7-25/h5-6,9-12,30H,2-4,7-8H2,1H3,(H,27,28,29)
InChIKey
JSKJFDXTKYWPAH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(2-chloro-3-(1-cyclopropyl-8-methoxy-3H-pyrazolo[3,4-c]isoquinolin-7-yl)-4-fluorophenyl)-3-fluoropropane-1-sulfonamide
CAS: 1581764-31-9
CID: 73427153
Formula: C23H21ClF2N4O3S
MW: 507.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight507.0
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass506.0990957
Monoisotopic Mass506.0990957
Topological Polar Surface Area105 Ų
Heavy Atom Count34
Formal Charge0
Complexity817
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M11364-01CUDC-907
M16553-01XEN-907
M12747-01EBI-1051
M13319-01EBI-2511

Alternative Products

CatalogName
T70424-01EBI-907
B7073-10JTE 907
530625JTE-907
MBS384569-01CUDC-907
BA4852-1EBI-2511
HY-111368EBI-1051
MLB65634-01XEN 907

Popular Products