Products for Research Use Only
RegisterLogin

CPI203

CAT: 1410-M11893-04Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M11893-04Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CPI 203 (TEN 010, JQ-2, RG-6146) is a primary amide analog of (+) -JQ1and a BET bromodomain inhibitor that shows cytotoxicity against MCL cell lines with GI50 of 0.1-0.3 uM.
CAS Number
1446144-04-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
399.897
Molecular Formula
C19H18ClN5OS
Notes
Research use only, not for human use.
Receptor
BRD4

Chemical Information

Cpi-203

a BET protein bromodomain inhibitor

CAS Number1446144-04-2
PubChem CID71291068
IUPAC Name2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetamide
Molecular FormulaC19H18ClN5OS
Molecular Weight399.9
XLogP2.9
Topological Polar Surface Area114
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count27
Formal Charge0
Complexity611
SMILES
CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)N)C4=CC=C(C=C4)Cl)C
InChI
InChI=1S/C19H18ClN5OS/c1-9-10(2)27-19-16(9)17(12-4-6-13(20)7-5-12)22-14(8-15(21)26)18-24-23-11(3)25(18)19/h4-7,14H,8H2,1-3H3,(H2,21,26)/t14-/m0/s1
InChIKey
QECMENZMDBOLDR-AWEZNQCLSA-N
Chemical Structure
2D Structure
2D structure of Cpi-203
CAS: 1446144-04-2
CID: 71291068
Formula: C19H18ClN5OS
MW: 399.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight399.9
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass399.0920591
Monoisotopic Mass399.0920591
Topological Polar Surface Area114 Ų
Heavy Atom Count27
Formal Charge0
Complexity611
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M12987-01CPI703

Alternative Products

CatalogName
GTR19163205-01CPI203
BUP13055-01(S) -CPI203
574644CPI203-rac
TBI4048-5MGCPI203, BET bromodomain inhibitor

Popular Products