Products for Research Use Only
RegisterLogin

MK-8722

CAT: 1410-M11645-04Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M11645-04Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, selective, allosteric pan-AMPK activator with EC50 of 1-60 nM for all 12 mammalian AMPK isoforms.
CAS Number
1394371-71-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
449.891
Molecular Formula
C24H20ClN3O4
Notes
Research use only, not for human use.
Receptor
AMPK

Chemical Information

MK-8722

an AMP-activated protein kinase activator

CAS Number1394371-71-1
PubChem CID89558344
IUPAC Name(3R,3aR,6R,6aR)-6-[[6-chloro-5-(4-phenylphenyl)-1H-imidazo[4,5-b]pyridin-2-yl]oxy]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol
Molecular FormulaC24H20ClN3O4
Molecular Weight449.9
XLogP3.8
Topological Polar Surface Area89.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity645
SMILES
C1[C@H]([C@@H]2[C@H](O1)[C@@H](CO2)OC3=NC4=NC(=C(C=C4N3)Cl)C5=CC=C(C=C5)C6=CC=CC=C6)O
InChI
InChI=1S/C24H20ClN3O4/c25-16-10-17-23(28-24(26-17)32-19-12-31-21-18(29)11-30-22(19)21)27-20(16)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-10,18-19,21-22,29H,11-12H2,(H,26,27,28)/t18-,19-,21-,22-/m1/s1
InChIKey
XQMNBTZLYOOAGA-UGESXGAOSA-N
Chemical Structure
2D Structure
2D structure of MK-8722
CAS: 1394371-71-1
CID: 89558344
Formula: C24H20ClN3O4
MW: 449.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight449.9
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass449.1142338
Monoisotopic Mass449.1142338
Topological Polar Surface Area89.5 Ų
Heavy Atom Count32
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M14568-01MK-0752
M12381-01MK-6169
M11576-01MK-8825
M10761-01MK-1064
M10626-01MK-8353
M10202-01MK-4074
M10091-01MK-3577
M10025-01MK-8033
M16688-01MK-4101
M16496-01MK-8141

Alternative Products

CatalogName
MBS132808MK-8722
UFC37171-01MK 8722
324068-01MK
167912Midkine (MK, MK1, MK-1, MK 1) discontinued
MBS131426MK-4101 (MK 4101; MK4101)
MBS131418Doravirine (MK-1439; MK1439; MK 1439)
456310-01MK 677
MKB78162-01MK-0674
A3615-10MK-3207
BA5198-1MK-5046

Popular Products