Products for Research Use Only
RegisterLogin

GDC-0810

CAT: 1410-M11510-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M11510-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GDC-0810 (ARN-810, Brilanestrant) is a non-steroidal, orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM (ER-α degradation) .
CAS Number
1365888-06-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
446.9006
Molecular Formula
C26H20ClFN2O2
Notes
Research use only, not for human use.
Receptor
ERα

Chemical Information

Brilanestrant

ARN-810 has been used in trials studying the basic science and treatment of Breast Cancer.

CAS Number1365888-06-7
PubChem CID56941241
IUPAC Name(E)-3-[4-[(E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-enyl]phenyl]prop-2-enoic acid
Molecular FormulaC26H20ClFN2O2
Molecular Weight446.9
XLogP7.4
Topological Polar Surface Area66
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count32
Formal Charge0
Complexity719
SMILES
CC/C(=C(/C1=CC=C(C=C1)/C=C/C(=O)O)\C2=CC3=C(C=C2)NN=C3)/C4=C(C=C(C=C4)F)Cl
InChI
InChI=1S/C26H20ClFN2O2/c1-2-21(22-10-9-20(28)14-23(22)27)26(18-8-11-24-19(13-18)15-29-30-24)17-6-3-16(4-7-17)5-12-25(31)32/h3-15H,2H2,1H3,(H,29,30)(H,31,32)/b12-5+,26-21+
InChIKey
BURHGPHDEVGCEZ-KJGLQBJMSA-N
Chemical Structure
2D Structure
2D structure of Brilanestrant
CAS: 1365888-06-7
CID: 56941241
Formula: C26H20ClFN2O2
MW: 446.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight446.9
XLogP37.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass446.1197337
Monoisotopic Mass446.1197337
Topological Polar Surface Area66 Ų
Heavy Atom Count32
Formal Charge0
Complexity719
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M11952-01GDC-0994
M11806-01GDC-0339
M11585-01GDC-0084
M10718-01GDC-0425
M16507-01GDC-0879
M11159-01GDC-0032
M39427-01GDC-1971
M12490-01GDC-0927
M13203-01GDC-0077
M10694-01GDC-0575

Alternative Products

CatalogName
MBS5751572GDC-0810
FG137678-01GDC 0810
C13003Brilanestrant (GDC-0810)
A15958-10GDC-0810 10mg
A15958-5GDC-0810 5mg
MBS3841282-01GDC-0810 (Brilanestrant)
A15958-25GDC-0810 25mg
A15958-1GDC-0810 (Brilanestrant) 1mg
A15958-100GDC-0810 (Brilanestrant) 100mg
A15958-2GDC-0810 (Brilanestrant) 2mg

Popular Products