Products for Research Use Only
RegisterLogin

AZD-1979

CAT: 1410-M11025-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M11025-02Size:1 mL x 10 mM in DMSO
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, selective melanin concentrating hormone receptor 1 (MCH-R1) antagonist with binding Ki of 12.2 nM.
CAS Number
1254035-84-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
462.506
Molecular Formula
C25H26N4O5
Notes
Research use only, not for human use.
Receptor
MCHR

Chemical Information

(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)(3-(4-(2-oxa-6-azaspiro(3.3)hept-6-ylmethyl)phenoxy)-1-azetidinyl)methanone

AZD1979 is a carboxamide resulting from the formal condensation of the carboxy group of 5-(p-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylic acid with the amino group of 3-phenoxyazetidine and in which the phenoxy group has been substituted at the para- position by a 2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl group. It is a melanin concentrating hormone receptor 1 (MCHr1) antagonist. It has a role as a melanin-concentrating hormone receptor antagonist. It is an aromatic ether, an azaspiro compound, a carboxamide, an oxaspiro compound, a member of oxetanes, an oxadiazole and a N-acylazetidine. It is a conjugate base of an AZD1979(1+).

CAS Number1254035-84-1
PubChem CID49801838
IUPAC Name[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-[3-[4-(2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy]azetidin-1-yl]methanone
Molecular FormulaC25H26N4O5
Molecular Weight462.5
XLogP2
Topological Polar Surface Area90.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count34
Formal Charge0
Complexity706
SMILES
COC1=CC=C(C=C1)C2=NN=C(O2)C(=O)N3CC(C3)OC4=CC=C(C=C4)CN5CC6(C5)COC6
InChI
InChI=1S/C25H26N4O5/c1-31-19-8-4-18(5-9-19)22-26-27-23(34-22)24(30)29-11-21(12-29)33-20-6-2-17(3-7-20)10-28-13-25(14-28)15-32-16-25/h2-9,21H,10-16H2,1H3
InChIKey
BKKPIQPFRAPEAY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)(3-(4-(2-oxa-6-azaspiro(3.3)hept-6-ylmethyl)phenoxy)-1-azetidinyl)methanone
CAS: 1254035-84-1
CID: 49801838
Formula: C25H26N4O5
MW: 462.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight462.5
XLogP32
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass462.19031994
Monoisotopic Mass462.19031994
Topological Polar Surface Area90.2 Ų
Heavy Atom Count34
Formal Charge0
Complexity706
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M14126-01AZD-8309
M14063-01AZD 9272
M13197-01AZD-4573
M12809-01AZD-0156
M10725-01AZD-8165
M10172AZD 9164
M27961-01AZD-5672
M20665-01AZD-7648
M16832-01AZD-9819
M16745-01AZD-7325

Alternative Products

CatalogName
MBS3601025AZD-1979
MPH01237hsa-miR-1979 Primers
NC44330-01AZD 1480
HEC15881-01AZD-26
ULB35141-01AZD 1283
WBC27045-01AZD 8186
FE18067-01AZD 1152
TQC80954-01AZD 6642
FA64951-01AZD 4547
FA153806-01AZD 2858

Popular Products