Ivacaftor hydrate

• Description:

  Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  410.506

• Molecular Formula:

  C24H30N2O4

• Notes:

  Research use only, not for human use.

• Receptor:

  CFTR

• CAS Number:

  1134822-07-3