Products for Research Use Only
RegisterLogin

CI-994

CAT: 1410-M10439-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M10439-02Size:1 mL x 10 mM in DMSO
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, selective class I HDAC inhibitor with IC50 of 0.9/0.9/1.2 uM for HDAC1/2/3, respectively.
CAS Number
112522-64-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
269.2985
Molecular Formula
C15H15N3O2
Notes
Research use only, not for human use.
Receptor
HDAC1|HDAC2|HDAC3

Chemical Information

Tacedinaline

Tacedinaline is a benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers. It has a role as an antineoplastic agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a member of acetamides, a member of benzamides and a substituted aniline. It is functionally related to a 1,2-phenylenediamine.

CAS Number112522-64-2
PubChem CID2746
IUPAC Name4-acetamido-N-(2-aminophenyl)benzamide
Molecular FormulaC15H15N3O2
Molecular Weight269.30
XLogP1.3
Topological Polar Surface Area84.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity351
SMILES
CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N
InChI
InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)
InChIKey
VAZAPHZUAVEOMC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tacedinaline
CAS: 112522-64-2
CID: 2746
Formula: C15H15N3O2
MW: 269.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight269.30
XLogP31.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass269.116426730
Monoisotopic Mass269.116426730
Topological Polar Surface Area84.2 Ų
Heavy Atom Count20
Formal Charge0
Complexity351
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M23460-01SDZ WAG 994
M10395-01CI-966
M22266-01CI 75300
M13094-01CI-1044
M10507-01CI-976
M16865-01CI-947
M37505-01CI 169369
M10394-01CI-966 hydrochloride
M21919-01Epidermal growth factor receptor (994-1002) acetyl/amide
M14261-01AY-9944

Alternative Products

CatalogName
1742-10CI-994
MBS132372-01CI 994
205997Tacedinaline (CI-994)
TBI2125-10MGCI-994, HDAC inhibitor
C-2606CI-994, Free Base [CAS# 112522-64-2]
MBS3613137-01SDZ WAG 994
167793-01CI-994 (4- (Acetylamino) -N- (2-aminophenyl) benzamide, Acetyldinaline, Gö 5549, PD 123654) discontinued
sc-59956Mucin 2 (994/152)

Popular Products