AMG-208

CAT: 1410-M10027-01Size: 1 gDry Ice: NoHazardous: No

CAT#:1410-M10027-01Size:1 g

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

AMG-208 is a potent, small-molecule c-Met inhibitor with IC50 of 5.2 nM against wt MET kinase, also inhibits VEGFR2 with IC50 of 112 nM.

CAS Number

1002304-34-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

383.4027

Molecular Formula

C22H17N5O2

Notes

Research use only, not for human use.

Receptor

C-Met

1002304-34-8

PubChem

cas	1002304-34-8
modify	2026-05-17
description	AMG-208 is a member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer. It has a role as an antineoplastic agent and a c-Met tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether and a triazolopyridazine.
synonyms	AMG-2081002304-34-8AMG 208AMG208 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Y2SR66P7VM 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline Quinoline, 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]- AMG 208 [WHO-DD]+ 15 more
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