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Neboglamine

CAT: 0804-HY-114753-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114753-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neboglamine (CR-2249; XY-2401) is a modulator for N-methyl-D-aspartate (NMDA) receptor. Neboglamine increases the levels of fos-like immunoreactivity (FLI) -positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models,.restores NMDA -mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion[1].
CAS Number
163000-63-3
Product Name Alternative
CR-2249; XY-2401
UNSPSC
12352211
Hazard Statement
H302
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neboglamine.html
Smiles
OC(CC[C@H](N)C(NC1CCC(C)(CC1)C)=O)=O
Molecular Formula
C13H24N2O3
Molecular Weight
256.34
Precautions
P264-P270-P330-P501
References & Citations
[1]Chiusaroli R, et al., Antipsychotic-like effects of the N-methyl-D-aspartate receptor modulator neboglamine: an immunohistochemical and behavioural study in the rat. Pharmacol Res. 2010 May;61 (5) :430-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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