Neoseptin 3

• Description :

  Neoseptin 3 is a Toll-like receptor 4/myeloid differentiation factor 2 (mTLR4/MD-2) agonist with an EC50 of 18.5 μM.

• CAS Number :

  [1622863-21-1]

• UNSPSC :

  12352005

• Hazard Statement :

  H413

• Target :

  Toll-like Receptor (TLR)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Neoseptin_3.html

• Purity :

  99.21

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  CC(C)(C)OC([C@H](CCC1=CC=CC=C1)NC(C2=CC(CCC3=CC=C(O)C=C3)=C(N)C=C2)=O)=O

• Molecular Formula :

  C29H34N2O4

• Molecular Weight :

  474.59

• Precautions :

  H413

• References & Citations :

  [1]Wang Y, et al. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc Natl Acad Sci U S A. 2016 Feb 16;113 (7) :E884-93.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  TLR4