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Recombinant Human Augurin (ECRG4), partial

CAT: 0399-CSB-EP887957HUa2-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-EP887957HUa2-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Esophageal cancer-related gene 4 protein; ECRG4
Abbreviation
Recombinant Human ECRG4 protein, partial
Gene Name
ECRG4
UniProt
Q9H1Z8
Expression Region
71-132aa
Organism
Homo sapiens (Human)
Target Sequence
QLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPR
Tag
N-terminal 6xHis-SUMO-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Cancer
Relevance
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
20.8 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

UniProtKB · Q9H1Z8

Augurin

AUGN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H1Z8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ECRG4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D3DVK2
Protein keywords

Cellular component

Cell membraneCytoplasmMembraneSecreted

PTM

Cleavage on pair of basic residues

Technical term

Proteomics identificationReference proteome

Domain

Signal

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