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PG106

CAT: 0804-HY-P1209Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1209Size:1 Each
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Description
PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].
CAS Number
944111-22-2
UNSPSC
12352209
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pg106.html
Solubility
10 mM in DMSO
Smiles
[Ac-{Nle}-D-{Bal}-{D-Nal}-RWK-NH2(Lactambridge:Asp2-Lys7)]
Molecular Formula
C51H69N13O9
Molecular Weight
1008.18
References & Citations
[1]Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC3R

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