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α-Conotoxin EIIB

CAT: 0804-HY-P5852Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-P5852Size:Inquire
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UNSPSC Description
α-Conotoxin EIIB (Alpha-conotoxin EIIB) is a toxin peptide that can be obtained from Conus ermineus. α-Conotoxin EIIB binds to nAChR (Ki=2.2 nM). α-Conotoxin EIIB can be used in the study of neurological diseases such as schizophrenia, drug addiction, Alzheimer's disease, and Parkinson's disease[1].
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C(N1)CCC1=O)N[C@H](C(N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H]4C)=O)CCC3)=O)CC5=CNC=N5)=O)CC6=CNC7=CC=CC=C67)=O)CSSC[C@H](NC8=O)C(N)=O)=O)CSSC[C@H](NC4=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H]8CCCNC(N)=N)=O)CC(N)=O)=O)CCCCN)=O)=O)=O)=O)CC(O)C2)=O)[C@@H](C)O
Molecular Weight
1754.99
References & Citations
[1]Echterbille J, et al. Discovery and characterization of EIIB, a new α-conotoxin from Conus ermineus venom by nAChRs affinity capture monitored by MALDI-TOF/TOF mass spectrometry. Toxicon. 2017 May;130:1-10.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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