Products for Research Use Only

Human CCL16 Recombinant Protein

CAT: 0908-RP2193H-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0908-RP2193H-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CCL16, also know as, Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1) is a member of the CC chemokine family. CCL16 is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. CCL16 has been found in high levels in the blood plasma of humans. CCL16 may be useful for trafficking eosinophils. This ligand has been found to have a functional affinity for H4 receptors that are expressed by eosinophils and mast cells. This chemokine has been shown to suppress rapid proliferation of myeloid progenitor cells.
Description
The Human CCL16 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human CCL16 applications are for cell culture, ELISA standard, and Western Blot Control. Human CCL16 yeast-derived recombinant protein can be purchased in multiple sizes. Human CCL16 Specifications: (Molecular Weight: 11.2 kDa) (Amino Acid Sequence: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ (97) ) (Gene ID: 601394) . For research use only.
Applications
Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
Homology
Gorilla gorilla gorilla (western lowland gorilla), Homo sapiens (human), Pan paniscus (pygmy chimpanzee), Pan troglodytes (chimpanzee)
Purity
>98% as visualized by SDS-PAGE analysis.
Molecular Weight
11.2kDa
Storage Temperature
-20°C