Swine CXCL10 (IP-10) Polyclonal Antibody - Biotinylated

• Background:

  CXCL10, also known as Interferon gamma-induced protein 10 or small-inducible cytokine B10, is a member of the C-X-C chemokine family. CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative) . ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 elicits its effects by binding to the cell surface chemokine receptor CXCR3.

• Description:

  The Swine CXCL10 (IP-10) polyclonal antibody is labeled and has been qualified for use in ELISA. It is the detection antibody in the Kingfisher Biotech Swine IL-13 ELISA. The Swine CXCL10 polyclonal antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine CXCL10 - None) (Canine CXCL10 - None) (Equine CXCL10 - None) (Feline CXCL10 - None) (Human CXCL10 - None) (Mouse CXCL10 - None) (Ovine CXCL10 - None) (Rabbit CXCL10 - None) (Rat CXCL10 - None) (Swine CXCL10 - Strong) . For research use only.

• Host:

  Goat

• Label:

  Biotin

• Applications:

  ELISA, ELISpot

• Purification:

  Antigen-affinity

• Homology:

  Sus scrofa (pig)

• Storage Temperature:

  2°C to 8°C

• Scientific Category:

  Antibody