KMT6 / EZH2 Rabbit mAb

• Background:

  Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

• Description:

  This is a KMT6 / EZH2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EZH 2; EZH1; EZH2; EZH2b; KMT 6; KMT6; KMT6A

• Swiss Prot:

  Q15910

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human KMT6 / EZH2

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC, ICC/IF, FC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:200, ICC/IF 1:50-1:200, FC 1:50

• Buffer:

  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG