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Palmitoleoyl-CoA

CAT: 0804-HY-137782Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137782Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Palmitoleoyl-CoA can be activated and transported into the mitochondria for metabolism, specifically for β-oxidation. Palmitoleoyl-CoA induces the cardiac mitochondrial membrane permeability transition, which causes mitochondrial dysfunction. Palmitoleoyl-CoA regulates metabolism via allosteric control of AMPK β1-isoforms[1][2].
CAS Number
18198-76-0
UNSPSC
12352204
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/palmitoleoyl-coa.html
Purity
93
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(CCCCCCC/C=C\CCCCCC)=O)=O)=O)O)C)=O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2
Molecular Formula
C37H64N7O17P3S
Molecular Weight
1003.93
Precautions
H302, H315, H319, H335
References & Citations
[1]Stephen L Pinkosky, et al. Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms. Nat Metab. 2020 Sep;2 (9) :873-881.|[2]Oyanagi E, et al., Palmitoleic acid induces the cardiac mitochondrial membrane permeability transition despite the presence of L-carnitine. Biochem Biophys Res Commun. 2015 Jul 17-24;463 (1-2) :29-36.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Enzyme
Clinical Information
No Development Reported

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