alpha-1,4-Galactosyltransferase (LgtC)

• UNSPSC Description:

  alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens[1][2].

• Target Antigen:

  Glycosyltransferase

• Type:

  Enzyme

• Related Pathways:

  Epigenetics

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/alpha-1-4-galactosyltransferase-lgtc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [alpha-1,4-Galactosyltransferase (LgtC)]

• References & Citations:

  [1]Kaczmarek R, et al. Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase. Glycoconj J. 2016 Dec;33(6):963-973.|[2]Iwamura K, et al. The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle. J Biol Chem. 2003 Nov 7;278(45):44429-38.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20°C for 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  52725-57-2