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V–C6–Bg-PhCl (TFA)

CAT: 0804-HY-162782ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162782ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria[1].
UNSPSC
12352211
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/v-c6-bg-phcl-tfa.html
Smiles
C[C@]1(N)C[C@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C(OC4=CC=C([C@H]([C@H](C(N[C@H]5CC(N)=O)=O)NC([C@@H](CC(C)C)NC)=O)O)C=C4Cl)C=C([C@H](C(N[C@@H]6C7=CC8=C(O)C=C7)=O)NC5=O)C=C3OC9=C(Cl)C=C([C@H]([C@@H](C(N[C@H](C(NCCCCCCNC(/N=C(N)/NC%10=CC=C(Cl)C=C%10)=N)=O)C%11=CC(O)=CC(O)=C8%11)=O)NC6=O)O)C=C9)O[C@@H](C)[C@H]1O.O=C(C(F)(F)F)O
Molecular Formula
C82H97Cl3F3N15O25
Molecular Weight
1856.09
References & Citations
[1]Rahn HP, et al. Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria. J Am Chem Soc. 2024 Aug 14;146 (32) :22541-22552.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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