RELM beta

CAT: 0209-M10-082-L500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0209-M10-082-L500Size:500 µg
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Description
RELMβ (Resistin-like molecule β/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver (Rajala, M. et al. J. Clin. Invest. Vol. 111, 225-230 (2003) ) . Interestingly the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokine Resistin and RELMβ. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant Murine RELMβ is an 18.0 kDa, consisting of two 83 amino acid residue chains.
Synonyms
Retnlb; Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik
NCBI Gene ID
57263
UniProt
Q99P86
Accession Number
NP_076370
Accession Number mRNA
NM_023881
Chromosomal Location
16 B5; 16 33.0 cM
Reactivity
Mouse
Cross Reactivity
Mouse, Pig, Intestinal Worm, Parasite
Sequence
MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
83
Form
Lyophilized
Molecular Weight
18 kDa
Host or Source
E. coli

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