MIA-2 (Melanoma inhibitory activity 2)

• Description:

  MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3) -like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity. Recombinant human MIA-2 is a 101 amino acid, 11.5 kDa protein comprising the MIA homologous N-terminal region of the full length MIA-2 protein.

• Synonyms:

  MIA2

• NCBI Gene ID:

  117153

• UniProt:

  Q96PC5

• Accession Number:

  NP_473365

• Accession Number mRNA:

  NM_054024

• Chromosomal Location:

  14q13.2

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Sequence:

  MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Data not available.

• Length:

  101

• Form:

  Lyophilized

• Molecular Weight:

  11.5 kDa

• Host or Source:

  E. coli