CXCL5 Protein

• Description:

  CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

• Synonyms:

  ENA-78 Protein; ENA78 Protein; SCYB5 Protein

• Accession Number:

  P42830

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Assay Protocol:

  See Datasheet send with the product

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 95 % as determined by SDS-PAGE

• Bioactivity:

  Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR2.

• Length:

  71

• Form:

  Lyophilized or frozen liquid

• Buffer:

  80% acetonitrile, 0.1% TFA, 20% H2O

• Reconstitution:

  See Datasheet

• Molecular Weight:

  8 kDa

• Storage Conditions:

  Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

• Host or Source:

  E.coli