CXCL14 / BRAK Protein

• Description:

  CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs) . CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.

• Synonyms:

  BMAC Protein; bolekine Protein; BRAK Protein; KEC Protein; KS1 Protein; MIP-2g Protein; MIP2G Protein; NJAC Protein; PSEC0212 Protein; SCYB14 Protein; UNQ240/PRO273 Protein

• Accession Number:

  O95715

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Assay Protocol:

  See Datasheet send with the product

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 90 % as determined by SDS-PAGE

• Bioactivity:

  Data not available

• Length:

  77

• Form:

  Lyophilized or frozen liquid

• Buffer:

  100mM NaH2PO4, 1M NaCl, pH 6.5.

• Reconstitution:

  See Datasheet

• Molecular Weight:

  15 kDa

• Storage Conditions:

  Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

• Host or Source:

  E.coli