Recombinant CX3CR1 Monoclonal Antibody

• Background:

  CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12) .

• Abbreviation:

  CX3CR1

• UniProt:

  P49238

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human CX3CR1 fragment

• Target:

  GPR; CCRL; GPRV; CX3CR; CMKDR; CMKBRL; CX3CR1; CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28; Beta chemokine receptor-like 1; CMK-BRL1; CMK-BRL-1; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; fractalkine receptor; G-protein coupled receptor 13

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A576

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Microbiology; Tags & Cell Markers; Immunology; Neuroscience; Cancer

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  40 kDa

• Observed Molecular Weight:

  50 kDa

• Isotype:

  IgG, κ